Pathology of Testicular and Penile Neoplasms by Maurizio Colecchia

Author:Maurizio Colecchia
Language: eng
Format: epub
Publisher: Springer International Publishing, Cham

Miscellaneous Tumors

Tumors having neither a germ cell nor sex cord/stromal origin are listed in the 2004 WHO classification [4] under this heading.

Malignant Lymphoma and Plasmocytoma

Primary malignant non-Hodgkin lymphomas (NHL) of the testis are defined as isolated manifestations of lymphatic malignancies in the testis without generalized nodal manifestation.

Epidemiology

In different series, 1–7 % of testicular tumors are NHL; nevertheless, they are the most frequent tumors after the age of 50 and also the most frequent bilateral tumors (20–30 %). Testicular NHL accounts for 1–2 % of all lymphomas and has an incidence of 0.26/100,000 [131]. Patients are mostly older than 60 years; in children NHL is less frequent [131].

Solitary extramedullary plasmocytoma of the testis is, with some 60 reported cases, much less frequent than other testicular NHL. The age at diagnosis ranges from 26 to 83 years, although the mean age at diagnosis is 60 years (Fig. 6.74) [132, 133].

Fig. 6.74Plasmacytoma of testis. The plasmacytoid nature of the tumor cells is highlighted by the MUM-1 positive reaction (Published with kind permission of ©Maurizio Colecchia 2015. All Rights Reserved)

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